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Search Results for " ulcerative colitis "

20

Compounds

Cat No. Product Name Synonyms Targets
T2S0342 Armillarisin A Others , Interleukin
Armillarisin A enhancing the role of macrophages, inhibiting bacteria growth, improving the protein metabolism, and regulating liver function.
T22344 Icatibant Acetate Bradykinin Receptor
Icatibant Acetate, an antagonist of the bradykinin B2 receptor, is used in the treatment of hereditary angioedema.
T35664 Tetracosactide acetate Others
Cosyntropin (acetate) stimulates the release of corticosteroids such as cortisol from the adrenal gland.
T20615 Olsalazine Dipentium,Salicylic acid Others
Olsalazine (Dipentium), an anti-inflammatory drug, is used in the treatment of inflammatory bowel disease. It is also a novel DNA hypomethylating agent.
T9377 ASK1-IN-2 Apoptosis , ASK , MAPK
ASK1-IN-2 is a potent and orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with an IC50 of 32.8 nM. ASK1-IN-2 can potentially be used as a therapeutic strategy for ulcerative colitis[1].
TN1084 1,3,5,8-Tetrahydroxyxanthone Desmethylbellidifolin Anti-infection
1,3,5,8-Tetrahydroxyxanthone (Desmethylbellidifolin) is a natural xanthone extracted from Gentianella acuta. 1,3,5,8-Tetrahydroxyxanthone has antispasmodic effect and anti-inflammatory activity. Dimethylbellidifolin show...
T4084 Sibofimloc VRT-1353385,Antibiotic-202,Antibiotic 202 Antibacterial , Antibiotic
Sibofimloc (Antibiotic-202), an antibiotic compound, is used in treating bacterial infections.
T2718 Palmatine chloride Others , Indoleamine 2,3-Dioxygenase (IDO) , Aurora Kinase
Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties.
T31964 Glycolithocholic acid Lithocholic acid glycine conjugate,Lithocholylglycine Others
Glycolithocholic acid (Lithocholic acid glycine conjugate) is a glycine conjugate of lithocholic acid.
T5S0802 Palmatine Berbericinine,Burasaine Indoleamine 2,3-Dioxygenase (IDO) , AChR , AChE , Aurora Kinase
1. Palmatine (Burasaine) is an inhibitor of dopamine generation. 2. Palmatine could potentially be developed for the treatment of flavivirus infections. 3. Palmatine has been used in the treatment of jaundice, dysentery,...
T4602 Hydrocortisone hemisuccinate Hydrocortisone 21-he,hydrocortisone 21-hemisuccinate*free acid,Hydrocortisone 21-hemisuccinate Glucocorticoid Receptor , Others , Interleukin
Hydrocortisone hemisuccinate (hydrocortisone 21-hemisuccinate*free acid) is a corticosteroid used as an analytical and chromatography reagent.
T3147 Pyrrolidinedithiocarbamate ammonium PDTC,Pyrrolidinedithiocarbamate,APDC,1-Pyrrolidinedithiocarboxylic acid ammonium salt,Ammonium pyrrolidinedithiocarbamate NF-κB
Pyrrolidinedithiocarbamate ammonium (1-Pyrrolidinedithiocarboxylic acid ammonium salt), a selective NF-κB inhibitor, inhibits translation of nitric oxide synthase mRNA to prevent induction.
T70084 Dersalazine Dersalazine Free Base IL Receptor , Platelet aggregation
Dersalazine (Dersalazine Free Base), an inhibitor of platelet-activating factor, exerts intestinal anti-inflammatory activity in different rodent types of colitis by down-regulating IL-17 expression, with potential effic...
T3620 Solcitinib GLPG-0778,GSK-2586184 JAK
Solcitinib (GLPG-0778) (GSK2586184, GLPG0778) is a JAK1 inhibitor. Solcitinib may be potentially used for the treatment of psoriasis, ulcerative colitis, and systemic lupus erythematosus.
T35898 Izencitinib TD-1473,JNJ-8398 JAK
Izencitinib (JNJ-8398) is an orally active and gut-selective JAK inhibitor with potential anti-inflammatory activity for the study of ulcerative colitis and Crohn;s disease.
T1544 Olsalazine disodium Dipentum,Olsalazine Sodium Others , COX , Antibacterial , Antibiotic
Olsalazine disodium (Dipentum) is bioconverted to 5-aminosalicylic acid (5-ASA) in the colon and has anti-inflammatory activity in ulcerative colitis.
T9914 Vedolizumab Integrin
Vedolizumab is a humanized monoclonal antibody that targets the α4β7 integrin for the treatment of Crohn's disease and ulcerative colitis.
T10208 A-69412 N-1-(Fur-3-ylethyl)-N-hydroxyurea Lipoxygenase
A-69412 (N-1-(Fur-3-ylethyl)-N-hydroxyurea) is a reversible, specific inhibitor of the hydrophilic 5-lipoxygenase. It has the potential to treat ulcerative colitis and asthma, and possibly other inflammatory and allergic...
T64334 Glycolithocholic acid, sodium salt Others
Glycolithocholic acid sodium salt, the sodium form of Glycolithocholic acid, is a glycine-conjugated secondary bile acid utilized in diagnosing ulcerative colitis (UC), non-alcoholic steatohepatitis (NASH), and primary s...
T2735 5-Acetylsalicylic acid 5-acetyl-2-hydroxybenzoic acid Others
5-Acetylsalicylic acid (5-acetyl-2-hydroxybenzoic acid) has anti-inflammatory effects and can be used to treat inflammatory bowel disease, including ulcerative colitis, inflamed anus or rectum, and to maintain remission ...

Compounds

Armillarisin A
T2S0342
Synonym:
Target: Others, Interleukin
Icatibant Acetate
T22344
Synonym:
Target: Bradykinin Receptor
Tetracosactide acetate
T35664
Synonym:
Target: Others
Olsalazine
T20615
Synonym: Dipentium,Salicylic acid
Target: Others
ASK1-IN-2
T9377
Synonym:
Target: Apoptosis, ASK, MAPK
1,3,5,8-Tetrahydroxyxanthone
TN1084
Synonym: Desmethylbellidifolin
Target: Anti-infection
Sibofimloc
T4084
Synonym: VRT-1353385,Antibiotic-202,Antibiotic 202
Target: Antibacterial, Antibiotic
Palmatine chloride
T2718
Synonym:
Target: Others, Indoleamine 2,3-Dioxygenase (IDO), Aurora Kinase
Glycolithocholic acid
T31964
Synonym: Lithocholic acid glycine conjugate,Lithocholylglycine
Target: Others
Palmatine
T5S0802
Synonym: Berbericinine,Burasaine
Target: Indoleamine 2,3-Dioxygenase (IDO), AChR, AChE, Aurora Kinase
Hydrocortisone hemisuccinate
T4602
Synonym: Hydrocortisone 21-he,hydrocortisone 21-hemisuccinate*free acid,Hydrocortisone 21-hemisuccinate
Target: Glucocorticoid Receptor, Others, Interleukin
Pyrrolidinedithiocarbamate ammonium
T3147
Synonym: PDTC,Pyrrolidinedithiocarbamate,APDC,1-Pyrrolidinedithiocarboxylic acid ammonium salt,Ammonium pyrrolidinedithiocarbamate
Target: NF-κB
Dersalazine
T70084
Synonym: Dersalazine Free Base
Target: IL Receptor, Platelet aggregation
Solcitinib
T3620
Synonym: GLPG-0778,GSK-2586184
Target: JAK
Izencitinib
T35898
Synonym: TD-1473,JNJ-8398
Target: JAK
Olsalazine disodium
T1544
Synonym: Dipentum,Olsalazine Sodium
Target: Others, COX, Antibacterial, Antibiotic
Vedolizumab
T9914
Synonym:
Target: Integrin
A-69412
T10208
Synonym: N-1-(Fur-3-ylethyl)-N-hydroxyurea
Target: Lipoxygenase
Glycolithocholic acid, sodium salt
T64334
Synonym:
Target: Others
5-Acetylsalicylic acid
T2735
Synonym: 5-acetyl-2-hydroxybenzoic acid
Target: Others
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TargetMol